Akademik Kadro

Doç. Dr. Aslı Kumbasar

Akademik dereceler ve çalışma deneyimi

Yrd Doç. Dr. – İstanbul Teknik Üniversitesi, Fen-Edebiyat Fakültesi, Moleküler Biyoloji ve Genetik Bölümü , İstanbul, 2010- halen.

Doktora Sonrası Araştırmacı – University of Maryland, Baltimore, Department of Anatomy and Neurobiology, Baltimore, MD, USA, 2006-2010.

Uzman Araştırmacı – TÜBİTAK, Gen Mühendisliği ve Biyoteknoloji Araştırma Merkezi, Gebze- Kocaeli, 2001-2006.

Doktora – Massachussetts Institute of Technology, Cambridge, MA, USA, Biyoloji, 2000.

Yüksek Lisans – Brandeis University, Waltham, MA, USA, Biyokimya 1990.

Lisans – Brandeis University, Waltham, MA, USA, Biyokimya 1990.

İlgi alanları

• Sinir kök hücrelerinde nörogenez ve gen ekspresyonu regülasyonu
• NFI transkripsiyon faktörlerinin çalışma mekanizmaları

Yayınlar

Uluslararası hakemli dergilerde yayımlanan makaleler :

1. Kumbasar A., C. Plachez, R. M. Gronostajski, L.J. Richards and E. D. Litwack (2009). Absence of the transcription factor Nfib delays the formation of the basilar pontine and other mossy fiber nuclei. J. Comp. Neurol. 513:98-112.
2. Erdag B., B.K. Balcioglu, A. Kumbasar, O. Celikbicak, G. Zeder-Lutz, D. Altschuh, B. Salih. and K. Baysal (2007). Novel short peptides isolated from phage display library inhibit vascular endothelial growth factor activity. Mol. Biotechnol. 35:51-64.
3. Korkmaz M., B.H. Guvenc, A. Bilir, O. Karal-Yilmaz, A. Kumbasar, J. Caferler and K. Baysal (2003). Isolation and culture of adult and fetal rabbit bladder smooth muscle cells and their interaction with biopolymers. J. Pediatr. Surg., 38:21-4.
4. Erdag B., B.K. Balcioglu, A. Kumbasar and B. Cirakoglu (2003). Detection of phage displayed peptides with blocking ability in vascular endothelial growth factor (VEGF) model. Adv. Exp. Med. Biol., 534:327-34.
5. Kleeff J., S. Wildi, A. Kumbasar, H. Friess, A. D. Lander and M. Korc (1999). Stable transfection of a glypican-1 antisense construct decreases tumorigenicity in PANC-1 pancreatic carcinoma cells. Pancreas, 19: 281-8.
6. Kleeff J., T. Ishiwata, A. Kumbasar, H. Friess, M. W. Buchler, A. D. Lander and M. Korc. (1998). The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer. J. Clin. Invest., 102: 1662-73.
7. Litwack E. D., J. K. Ivins, A. Kumbasar, S. Paine-Saunders, C. S. Stipp and A. D. Lander (1998). Expression of the heparan sulfate proteoglycan glypican-1 in the developing rodent. Developmental Dynamics, 211: 72-87.
8. Ivins J. K., E. D. Litwack, A. Kumbasar, C. S. Stipp and A. D. Lander (1997). Cerebroglycan, a developmentally regulated cell-surface heparan sulfate proteoglycan, is expressed on developing axons and growth cones. Developmental Biology, 184: 320-32.
9. Litwack E. D., C. S. Stipp, A. Kumbasar and A. D. Lander (1994). Neuronal expression of glypican, a cell-surface glycosylphosphatidylinositol-anchored heparan sulfate proteoglycan, in the adult rat nervous system. J. Neurosci., 14: 3713-24.

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