Akademik Kadro

Doç.Dr. Ceren Çıracı

Akademik Deneyim
Y.Doç.Dr. – İstanbul Teknik Üniversitesi, Moleküler Biyoloji ve Genetik B., (Şubat 2015- )
Doktora Sonrası Araştırmacı (Post-doc) – The University of Iowa, Internal Medicine Department, Inflammation Program, Coralville, IA, USA, 2011-2014.
Doktora Sonrası Ziyaretçi Araştırmacı – Georgetown University Department of Biochemistry and Molecular & Cellular Biology, Washington DC, USA, 2011.
Doktora – Iowa State University of Science and Technology, Ames, IA, USA, Interdisciplinary Genetics, 2004-2010.
Yüksek Lisans – Bilkent University, Ankara, Türkiye, Molecular Biology and Genetics, 2002-2004.
Lisans – Ankara University, Ankara, Türkiye, Biology, 1998-2002.

İlgi alanları
• Hücre içi receptörlerin (NOD-like Receptors) bağışıklık sistemi üzerine etkileri, çalışma mekanizmaları ve moleküler genetic regülasyonları
• Makrofaj, Dendritik hücreler ve T hücrelerindeki genlerin fonksiyon ve ekspresyonlarının regülasyonu

Yayınlar
• Janczy JR*, Ciraci C*, Haasken S, Olivier A.K., S. Cassel SL and Sutterwala F.S. Immune complexes inhibit interleukin-1 secretion and inflammasome activation. (The Journal of Immunology, 2014, Oct 15, doi:10.4049). [*authors equally contributed].
• Ciraci C, Janczy JR, Sutterwala FS, and Cassel SL. Control of innate and adaptive immunity by the inflammasome. Microbes Infect. 2012 Nov;14(14):1263-70. Review.
• Kaiser MG, Block SS, Ciraci C., Fang W, Sifri M, Lamont SJ. Effects of dietary vitamin E type and level on lipopolysaccharide-induced cytokine mRNA expression in broiler chicks. Poult Sci. 2012 Aug;91(8):1893-8.
• Ciraci C, Sutterwala FS. Inhibitors of apoptosis proteins and IL-1β: a tangled relationship. Immunity. 2012 Feb 24;36(2):155-7. Review.
• Lian L, Ciraci C, Chang G, Hu J, Lamont SJ. NLRC5 knockdown in chicken macrophages alters response to LPS and poly (I:C) stimulation. BMC Vet Res. 2012 Mar 8;8:23
• Ciraci C, and Lamont SJ. Avian-specific TLRs and downstream effector responses to CpG-induction in chicken macrophages. Dev Comp Immunol. 2011 Mar;35(3):392
• Kumar S, Ciraci C., Redmond SB, Chuammitr P, Andreasen C, Palić D and Lamont SJ. Immune response gene expression in spleens of diverse chicken lines fed dietary immunomodulators. Poult Sci. 2011 May;90(5):1009-13.
• Ciraci C, Tuggle CK, Wannemuehler MJ, Nettleton D, Lamont SJ. Unique genome-wide transcriptome profiles of chicken macrophages exposed to salmonella-derived endotoxin. BMC Genomics. 2010 Oct 8;11:545
• Celikkaya H, Ciraci C, Oztas E, Avci ME, Ozturk M, Yagci T.Immunization with UV-induced apoptotic cells generates monoclonal antibodies against proteins differentially expressed in hepatocellular carcinoma cell lines. Hybridoma (Larchmt). 2007 Apr;26(2):55-61.
• Cheeseman JH, Kaiser MG, Ciraci C, Kaiser P, Lamont SJ. Breed effect on early cytokine mRNA expression in spleen and cecum of chickens with and without Salmonella enteritidis infection. Dev Comp Immunol. 2007 May;31(1):52-60.

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